Li Hui（Lecturer）

  Name：

Li Hui

Academic Title：

Lecturer

Advisor Type：

Master's Supervisor

  Department：

Department of   Biological and Energy Chemical Engineering

Research Interests：

Microbial   Metabolic Engineering, Genetic Engineering, Enzyme and Protein Engineering

  E-Mail：

lihui@upc.edu.cn

  Telephone：

15610458295

◎Educational Background

2004-2008,   Department of Biotechnology, School of Life Sciences, Shandong University,   Bachelor of Science

2008-2013,   State Key Laboratory of Microbial Technology, Shandong University, PhD in   Microbiology

◎Work Experience

2013 - School   of chemistry and chemical engineering, China University of Petroleum (East   China), lecturer

◎Research Direction

[1]   Biochemical Engineering

[2] Microbial   Metabolic Engineering

◎Research Project

[1]Natural   Science Foundation of China(31800075), Directional   regulationrole and mechanism of TALE-DNA scaffold-mediated multi-enzyme complexes   in welan gum biosynthesis, 2019/01-2021/12

[2] Shandong Provincial Natural   Science Foundation (ZR2015CL003), Optimization of the biosyntheis pathway of   Welan gum by multi-enzyme complexes，2015/08-2017/08

[3] Chinese Postdoc Fund (2014M551981)，The research   on biosynthesis pathway and regulation mechanism of welan gum based on   genomic sequencing，2014/01-2015/12

[4] Qingdao Postdoc Fund，Construction   of engineering strain with high yield of Welan gum and scaling-up of   fermentation process，2014/07-2016/01

[5] Fundamental Research Funds for the   Central Universities and the Development Fund of State Key Laboratory of   Heavy Oil Processing (20CX02202A)，Modification technology of biopolymer   Welan gum and development of its surface active derivatives, 2020/05-2022/04

[6] Fundamental Research Funds for the   Central Universities (18CX02124A)，Construction of engineering strain   with high yield of Welan gum based on the TALE-DNA scaffold-mediated   multi-enzyme complexes, 2018/01-2020/12

[7] Fundamental Research Funds for the   Central Universities (14CX02124A)，The research on biosynthesis pathway   and regulation mechanism of welan gum，2014/01-2015/12，

[8]863 Program   (2015AA020925), The biosynthesis pathway of Welan gum in Sphingomonas sp. WG   and construction the engineering strain，2015/01-2017/12

◎Representative Papers and Patents

1. Paper

[1] Hui Li, Mengqi Chen, Zaimei Zhang,   Benchao Li, Jianlin Liu, Han Xue, Sixue Ji, Zhongrui Guo, Jiqian Wang* and Hu   Zhu*.Hybrid Histidine Kinase WelA of Sphingomonas   sp. WG Contributes to WL Gum Biosynthesis and Motility, Frontiers in   Microbiology,2022, 13:792315.

[2]   Hui Li, Kehui Li,   Zhongrui Guo, Han Xue, Jing Li, Sixue Ji, Jiqian Wang *, Hu Zhu *. The   function of β-1,4-glucuronosyltransferase WelK in the sphingan WL gum   biosynthesis process in marine Sphingomonas   sp. WG, Marine Biotechnology, 2021, 23: 39-50

[3]   Hui Li, Jing Li, Xue   Jiao, Kehui Li, Yajie Sun, Wanlong Zhou, Yaling Shen, Jin Qian, Aiping Chang,   Jiqian Wang^*, Hu Zhu^*. Characterization of the   biosynthetic pathway of nucleotide sugar precursor UDP-glucose during   sphingan WL gum production in   Sphingomonas sp. WG. Journal of Biotechnology, 2019, 302:1-9.

[4]Munzer Ullah ^#, Hui Li ^#, Shi-Wei Sun,   Cai-Hong Weng, Hong Zhang, Hu Zhu^*.Polyvinyl alcohol   degradation by Bacillus cereus RA23   from oil sludge sample.3 BIOTECH,2019, 9:350.

[5] Hui Li, Jing Li, Wanlong Zhou, Xue   Jiao, Yajie Sun, Jiqian Wang^*, Hu Zhu^*. An efficient   production of a novel carbohydrate polymer Sphingan WL. Journal of Chemical   Technology and Biotechnology, 2018, 93: 3472-3482.

[6] Hui Li, Xue Jiao, Wanlong Zhou, Yajie   Sun, Wei Liu, Weiping Lin, Ao Liu, Aihua Song, Hu Zhu^*. Enhanced production   of total flavones from Inonotus baumii   by multiple strategies. Preparative Biochemistry and Biotechnology,   2018,48(2): 103-112.

2.Patent

[1]Li Hui; Zhu   Hu; Sun Yajie; Jiao Xue; Zhou Wanlong; Li Jing; A series of improved pBBR1MCS   plasmids and their application, 2019-06-04,, China, ZL201610867175.1

[2] Zhu Hu; Sun Shiwei; Li Hui; Liu   Ao; Zhou Wanlong; Dai Xiaoyun; Bu Xiangguo; Application of fig leaf extract   with Bacterial Quorum Sensing Inhibition Activity, 2019-12-17, China,   ZL201610001371.0

[3] Zhu Hu; Sun Shiwei; Li Hui; Liu   Ao; Dai Xiaoyun; Bu Xiangguo; Weng Caihong; A bacterial quorum sensing   inhibitor and its application, 2018-10-23, China, zl201610457296.9

[4] Zhu Hu; Sun Shiwei; Li Hui; Sun   Jiao; Zhou Wanlong; Liu Ao; The strain Rheinheimera   aquimaris isolated from marine sludge and its application, 2018-07-06,   China, ZL201510393657.3

[5] Zhu Hu; Li Hui; Feng Zhimei; Zhou   Wanlong; Sun Yajie; LV Jianren; A Strain and methods for producing Welan gum,   2018-05-08, China, ZL201410485635.5

[6] Zhu Hu; Sun Shiwei; Li Hui; Sun   Jiao; Liu Ao; Zhou Wanlong; Isolation, extraction, structural identification   and application of a novel quorum sensing inhibitor, 2017-08-11, China，ZL201510436013.8

[7] Ji Sixue, Wang Jiqian, Li Hui, Zhu   Hu, Xu Hai, Lu Teng. Biological oil displacement agent Welan gum and its oil   displacement system, 2021-02-05, China, ZL201910359615.6, 

◎Representative Works

[1] Hui Li, et   al. Biological Production of Welan gum. Chapter 4 in Book: Biomaterials-   Biological Production of Fuels and Chemicals. Editor: Rafael Luque, Chunping   Xu, Publisher: De Gruyter，2016, pages 73-94.

◎Awards and Honors

[1]The 6th   Shandong province “Internet plus” college students' innovation and   entrepreneurship competition  excellent tutor

◎Courses Offered

Undergraduate：《Molecular   Biology》《Microorganisms   and Human》

Postgraduate：《Genetic   Engineering》《Applied   Molecular Biology》

◎Student Training

1.        Supervise Postgraduate Students

Currently, there are 6 master   students. Among the 8 students who graduated, 3 work in biopharmaceutical   companies, 1 work in petroleum and petrochemical companies, 3 are engaged in   education and 1 is Ph.D. student.

2.Admissions Instructions：

Students majored in Bioengineering, Food   Science and Engineering, Chemical Engineering and Technology, Chemistry

◎Part-time Academic Job

[1] Reviewer   of Preparative Biochemistry and Biotechnology.